Learning

I find WPI’s Kwik-Cast handy for some things around the lab. When we were modest users, the price didn’t bother me too much. However, when we started going through so much of it, I wondered if there was a way to buy it that f...
I find WPI’s Kwik-Cast handy for some things around the lab. When we were modest users, the price didn’t bother me too much. However, when we started going through so much of it, I wondered if there was a way to buy it that fit our consumption level a bit better. Both of those pots together were about $50. (Body Double Fast Set – Trial Size, Reynolds Advanced Materials) These are the double-barreled syringes and mixing tips I bought. They’re from this company. 2mm x 8 Element, Needle Tip qty. 1-99 – $0.91 each (WPI charges about $2.90 per tip, about 318% more) qty. 100+ – $0.637 each (Buy 100 for $63.70. From WPI, 30 tips cost $87.00, 455% more) 4B19 Double barreled syringe qty. 1-99 – $1.953 each qty. 100+ – $1.367 each Here, you can see below that the WPI Kwik-Cast kit uses the same syringes and mixing tips, at least as far as I can tell. From WPI, each of these syringes (with contents) is $85. So you can buy the DIY stuff above ($50), 50 tips ($9.10 * 5 = $45.50), and 10 syringes ($19.53) for a grand total of $115.03. This would cost $850 + ($29 * 5 = $145) = $995.00 from WPI. Plus, with the DIY way, you’ll still have the vast majority of your silicone elastomer left over from the $50 kit. I’m not sure I’ll ever run out. The drawback of the DIY way is that you have to fill your own syringes, or have an undergrad do it for you. I used a couple of 5 mL syringes, and it took maybe a minute or two to do one syringe.
11 minutes ago
Publication of US psychiatry's updated diagnostic code has provoked renewed debate in recent weeks over the extent to which mental illness ought to be framed as a psychosocial or a biological problem. The answer of course is that it is b...
Publication of US psychiatry's updated diagnostic code has provoked renewed debate in recent weeks over the extent to which mental illness ought to be framed as a psychosocial or a biological problem. The answer of course is that it is both. A new Canadian study captures this interplay, showing how close friendships mitigate the risk for girls whose genes mean they are more vulnerable than average to depression. Mara Brendgen and her colleagues studied 294 pairs of twins aged ten years old (147 girls). Some of the twins were identical (they share the same genes), the others were non-identical (sharing just half their genes). Each twin pair was raised together in the same family. The researchers obtained ratings of the children's signs of depression from their teachers and classmates. They also gauged their close friendships by asking each child to nominate up to three best friends in their class, and to indicate who was their very best friend. Reciprocal nominations were a sign of mutual friendship. The children also answered questions about the quality of their friendships, including whether they do fun things together or get angry with each other. Consistent with past research, there was evidence of the role of genes in depression. That is, correlations in signs of depression were much higher between identical versus non-identical twins. If one of a pair of identical twins had signs of depression, this was taken as an indication that the second twin had genetic vulnerability for the condition. If one of a pair of non-identical twins showed signs of depression, this was also taken to mean the other twin had genetic vulnerability, but less so than in the case of identical twins. Here's the main result. Genetic vulnerability to depression in girls was less likely to manifest if they had at least one close friend. Stated differently, the apparent protective effect of having at least one close friend was magnified in girls who were genetically vulnerable to the condition. This means that for girls there was an interplay between genetic risk and the protective effect of friendship. This was not the case for boys. Friendships did appear to protect boys from depression, but this was not related in any way to their genetic vulnerability. Perhaps, the researchers surmised, there is a gender difference because "girls tend to rely more on social relationships as a source of self-definition and self-validation, and their friendships are also characterised by greater intimacy, self-disclosure, empathy and emotional support." Separate from any issues of genetic vulnerability, another gender difference was that boys, but not girls, showed an additive protective effect against depression of having more friends. The researchers said this may be because girls more often have intimate one-on-one friendships, whereas boys are more often part of friendship groups. Other details to emerge from the study: better quality friendships were more protective against depression (regardless of genetic vulnerability); genetic vulnerability to depression wasn't associated with the likelihood of a child having friends, but it was negatively associated with the perceived quality of their friendships. The study has some limitations, particularly the relatively small sample size, the reliance on observer ratings of depression, and the cross-sectional design, which means a causal role for friendships cannot be assumed. Also, the results may be specific to this age group. Despite these shortcomings, this is an innovative study on an important topic. Children who show signs of depression pre-adolescence are at heightened risk for having problems in their teens and beyond, so the more we understand about mitigating this risk, the better. The researchers said their results "emphasise the importance of teaching social interactional skills that promote positive relations with others to help prevent the development of depressive behaviour in childr
15 minutes ago
A massive blast ripped through an explosives factory Monday in eastern China, killing five people and leaving another 20 missing, state media reported. Rescue work was continuing at the site of the mid-morning ...
A massive blast ripped through an explosives factory Monday in eastern China, killing five people and leaving another 20 missing, state media reported. Rescue work was continuing at the site of the mid-morning ...
20 minutes ago
It's almost time for a new Xbox. Eight years have passed since Microsoft unveiled the Xbox 360, double the amount of time between the original Xbox debut in 2001 and its high-definition successor's launch in 2005. With the next-generatio...
It's almost time for a new Xbox. Eight years have passed since Microsoft unveiled the Xbox 360, double the amount of time between the original Xbox debut in 2001 and its high-definition successor's launch in 2005. With the next-generation Xbox expected to be revealed Tuesday, anticipation for the entertainment console's latest evolution is running high.
24 minutes ago
by Carol A. Westbrook In a recent editorial in the New England Journal of Medicine1, Drs. Stavert and Lott used the tem, "The Bystander Effect," to describe a new health care phenomenon, in which multiple physicians particip...
by Carol A. Westbrook In a recent editorial in the New England Journal of Medicine1, Drs. Stavert and Lott used the tem, "The Bystander Effect," to describe a new health care phenomenon, in which multiple physicians participate in the care of a patient, while none acknowledges primary responsibility for managing it.  In their example, a patient was hospitalized with an undiagnosed, complicated illness, and over 40 physicians were involved in his care, yet none stepped forward to take charge.The term "Bystander Effect" was coined after the 1964 stabbing murder of Kitty Genovese in New York City, which was witnessed by 38 people, none of whom intervened or called for help.  The term refers to the tendency of people to be less likely to offer help in emergency situations when other people are present. In other words, it's not my problem, someone else can take charge. Stavert and Lott argued that the Bystander Effect is becoming prevalent because of the way our system of hospital care has evolved.  But I have noticed it is beginning to appear in the outpatient setting as well, where it is eroding the quality of medical care while increasing its expense.  Consider Mr. Miller, a fictional patient referred to me for anemia. I ordered blood tests, referred him for a colonoscopy, and scheduled a return visit in 2 weeks.  During those two weeks, he also saw his cardiologist (heart), his orthopedist (joints), his urologist (prostate), his internist (blood pressure), his primary care physician (cholesterol).  Mr. Miller is elderly and retired. When I asked him what he does with his leisure time, and he replied,  "What free time? My wife and I spend most of our day in the doctor's office."   From my perspective, Mr. Miller received the expert attention of 7 highly trained medical specialists, and the best possible medical care in the world.  From his perspective, he has to deal with two more doctors, more prescription medications to use up his limited income, and no assurance that any of this will make him feel better or live longer. It is disheartening to see an elderly couple who measure out their days by the number of doctors' visits in a week. It is frustrating for their caregivers, who try their best to attend these multiple clinic visits.  And it is dangerous, as multiple physicians may give contradictory recommendations, prescribe medications that interact, and overlook test results ordered by another doctor.Mr. Miller is definitely getting more medical care than he would have received, say, 10 years ago.  But is he getting better care?  For that matter, is he even getting care? Think back to a simpler time when a patient had one doctor whom he knew personally and trusted, and who provided him with care, one human being to another.  Today it takes many more doctors to provide the same amount of care. There are several reasons that our health care system has evolved in this direction.  The major reason is economic.  There is a limit to how much Medicare or insurance will pay for a clinic visit, but there is no limit to the number of clinic visits.  Thus, the economic imperative tends toward increasing the number of doctor visits rather than the quality of the visits.  Today's doctor may have a quota of 15 to 25 patients per day if he wants to keep his job. Consequently, he does not have much time between appointments to make calls or send emails, and has little opportunity to get to know his patients as human beings.  Care suffers.  Physicians become bystanders. Another force leading to fragmentation is specialization. Treating a relatively healthy patient who has a single problem--such as a sore throat--is straightforward. The patient is examined, boxes are ticked in the electronic chart, and the prescription is electronically sent to the pharmacy.  But when a patient has health issues that cross the boundaries of many specialties, such as Mr. Miller, it is easier to reduce him to a collection of unr
25 minutes ago
(Written in 1932 on Spanish soil, mainly in the Mosque of Cordoba) BY MOHAMMED IQBAL I Chain of day and night Fashioner of events Basis of life and death Two tone silken thread Fiber...
(Written in 1932 on Spanish soil, mainly in the Mosque of Cordoba) BY MOHAMMED IQBAL I Chain of day and night Fashioner of events Basis of life and death Two tone silken thread Fiber of attributes Pitch of prospects Chain of day and night Sitting in judgment Setting a value on us When we're lacking Death is your destiny Death is my destiny What else is reality The flow of one age Neither day nor night All crafts vanish Black and white fade Annihilation the end II But in this form Hues of eternal life Splendor of man's love Love is life's base Death has no claim on love Love itself the tide Stemming the torrent Love is unnamed eras Love is Gabriel's breath Love is the Prophet of God Love is the Word of God Love is the radiant rose Love is raw wine Love the goblet of kings Love draws life's music Love is passion for life Love is fire of life III O Mosque of Cordoba Born of love with no past Color or stone or brick Harp or song or speech Man's passionate creation A drop of blood turns Even stone into hearts The heart's voice is joy Burning and melody You illuminate the heart My song burns the breast You draw man's heart To the presence of God But the passion of love For God is man's alone I spark man's passion Though his sight is finite His heart is wider than the sky So what if God has rights He doesn't earn the pain I am an Indian infidel Witness my fervor In my heart prayers On lips blessings Love is my flute Love is my song In my every bone "God is God" IV Witness of man's worth Your glory mirrors his soul Firm columns soar Palms in Syrian sands Sinai's light gleams roof Gabriel crowns the minaret A Muslim can never despair Standing where the Prophets stood His horizon infinite Tigris Danube Nile flood his veins Cup-bearer and horseman In love a warrior A sword's shadow his armor "There is no god but God" V You reveal man's secret Ardor of his days Dissolution of his nights His submission As is God's hand So is the believer's Man prospers on deeds He is clay and fire Divine within Free of both worlds His ambition small His purpose large Pure-hearted in war or peace God's compass revolves Around man's faith And the world is illusion Man of God is reason's horizon The harvest of love Fire of the gathering Heaven's passion VI Art lover's Mecca Faith's grandeur You made Andalusia holy Only Muslims mirror your grandeur O those Arab horsemen Pledged to truth Revealed this new secret People who embrace Faith Renounce the material They enlightened the West Yemen's scent persists Even today Arabia's music Lingers in Andalusia's breeze VII Alas for centuries No Calls to Prayer Echo the minaret In which valley At which destination Is love's caravan inducing frenzy As all Europe swept away the old order Repainted the face of the West So today those torrents stir Muslims A divine prophecy seals my lips But let us watch secrets surface From the ocean's depth Watch the sky change hue VIII A cloud drenched in twilight The sun scatters rubies A peasant's daughter sings Youth sails on heart's boat On the Guadalquivir Someone dreams of another age New order still veiled by fate Another dawn is
25 minutes ago
Law
Posted by D. Daniel Sokol Hideki Murakami (Graduate School of Business Administration, Kobe University) examines Dynamic Effect of Low-Cost Entry on the Conduct Parameter: An Early-Stage Analysis of Southwest Airlines and America West Ai...
Posted by D. Daniel Sokol Hideki Murakami (Graduate School of Business Administration, Kobe University) examines Dynamic Effect of Low-Cost Entry on the Conduct Parameter: An Early-Stage Analysis of Southwest Airlines and America West Airlines. ABSTRACT: The purpose of this research...
27 minutes ago
It's the fifth time in three days that North Korea has launched a projectile.
It's the fifth time in three days that North Korea has launched a projectile.
35 minutes ago
A wave of car bombings strikes Baghdad's Shiite areas and the southern city of Basra.
A wave of car bombings strikes Baghdad's Shiite areas and the southern city of Basra.
39 minutes ago
WASHINGTON (AP) — Secretary of State John Kerry is heading back to the Middle East this week to press his case for peace talks between Syrian rebels and President Bashar Assad's regime amid increasing signs the new U.S. strategy to ...
WASHINGTON (AP) — Secretary of State John Kerry is heading back to the Middle East this week to press his case for peace talks between Syrian rebels and President Bashar Assad's regime amid increasing signs the new U.S. strategy to halt the war is being undermined by Russia.
about 1 hour ago